Fall
1998
The Culprit is Cancer
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Gene
therapy trials all over the country are indicating it may be possible
to repair mutated genes by introducing into tumors normal copies
of the mutated gene that caused the tumor in the first place.
We
are in the early stages of "teaching" the human immune system to
fight cancer that has spread through the body. Tumor cells are being
surgically removed, modified in the lab, irradiated to prevent them
from growing, and used to make a vaccine against a patient's tumor.
And
we have made a major discovery right here at UCLA, where Dr. Dennis
Slamon's 12 years of work have led to an antibody that may control
a most aggressive form of breast cancer developed by some 30 percent
of women who have the disease.
We
are identifying more and more genes that are altered in cancer.
And we are harnessing technology to develop treatments that target
those genes exclusively.
Our
goal is to develop ways to prevent, detect and treat cancer - this
combination will ultimately eradicate the disease.
Research
cures cancer. More than eight million cancer survivors prove it.
We are moving research from the laboratory to the patient faster
and faster.
We
have won the battle to understand our enemy. We have proven that
we can not only treat cancer, but prevent it as well.
I think
we are seeing the beginning of the end of cancer.
For
information about ongoing clinical trails at UCLA,
please see the UCLA Jonsson Cancer Center's Web site at http://www.cancer.mednet.ucla.edu.
For
other clinical trails, contact the National Cancer Institute at
http://cancertrials.nci.nih.gov.
Gasson
is director of UCLA's Jonsson Comprehensive Cancer Center.
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